Wednesday, November 30, 2011

Malaysia advances new law banning street protests (AP)

KUALA LUMPUR, Malaysia ? Malaysian lawmakers approved a ban on street protests Tuesday after opposition legislators boycotted the vote and activists criticized the ban as repressive and a threat to freedom of assembly.

Prime Minister Najib Razak's ruling coalition says the Peaceful Assembly Act is intended to strike a balance between public order and the right to peaceful assembly. The act passed easily in Parliament's lower house after the boycott, and the law is expected to be enforced after Parliament's upper house, also dominated by the National Front coalition, approves it as early as next month.

But Malaysian and international rights groups describe it as repressive because it bans street rallies and imposes tough restrictions and penalties for demonstrators. The law was announced only last week, and some critics say the vote was rushed without proper public consultation.

About 500 lawyers and their supporters marched to Parliament hours before the vote, urging lawmakers to reject the bill and chanting "Freedom to the people" before police stopped most of them from entering the complex.

The new law would confine demonstrators mainly to stadiums and public halls. Depending on the venue, organizers may be required to give 10-day advance notification to police, who would determine whether the date and location are suitable.

Children under 15 and non-citizens would be barred from attending rallies, which also cannot be held near schools, hospitals, places of worship, airports or gasoline stations. Demonstrators who break the law can be fined 20,000 ringgit ($6,200).

V.K. Liew, a deputy Cabinet minister in Najib's office who received a protest note from the lawyers Tuesday, suggested that critics should not be too quick to criticize the law.

"We should look at it holistically, not piecemeal," Liew told reporters.

Opposition leader Anwar Ibrahim said he believed the Peaceful Assembly Act would be "more Draconian" than laws in Zimbabwe or Myanmar. Other opposition activists indicated they might challenge the law in court, insisting it breaches the people's constitutional rights.

Malaysian authorities have long been wary of political demonstrations. In July, police briefly arrested hundreds of protesters and fired tear gas at more than 20,000 people who marched in Kuala Lumpur to demand greater electoral transparency ahead of national polls widely expected next year.

Rights group Amnesty International on Monday called the Peaceful Assembly Act "a legislative attack on Malaysians' right to peaceful protest," while Human Rights Watch said the law was being pushed through Parliament with "undue haste."

___

Associated Press writer Eileen Ng contributed to this report.

Source: http://us.rd.yahoo.com/dailynews/rss/asia/*http%3A//news.yahoo.com/s/ap/20111129/ap_on_re_as/as_malaysia_protests

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Raiders get 6 FGs in 25-20 win over Bears

Oakland Raiders' Sebastian Janikowski (11) kicks a 37-yard field goal against the Chicago Bears during the third quarter of an NFL football game in Oakland, Calif., Sunday, Nov. 27, 2011. (AP Photo/Ben Margot)

Oakland Raiders' Sebastian Janikowski (11) kicks a 37-yard field goal against the Chicago Bears during the third quarter of an NFL football game in Oakland, Calif., Sunday, Nov. 27, 2011. (AP Photo/Ben Margot)

Oakland Raiders running back Michael Bush (29) runs past Chicago Bears defensive end Israel Idonije (71) during the third quarter of an NFL football game in Oakland, Calif., Sunday, Nov. 27, 2011. (AP Photo/Ben Margot)

Chicago Bears quarterback Caleb Hanie throws against the Oakland Raiders during the first quarter of an NFL football game in Oakland, Calif., Sunday, Nov. 27, 2011. (AP Photo/Paul Sakuma)

Chicago Bears quarterback Jay Cutler stand on the sideline as his team plays the Oakland Raiders during the first quarter of an NFL football game in Oakland, Calif., Sunday, Nov. 27, 2011. (AP Photo/Ben Margot)

(AP) ? Playing against a fill-in quarterback making his first career NFL start, the Oakland Raiders managed to win despite struggling to punch the ball into the end zone.

Sebastian Janikowski kicked a team-record six field goals and the Raiders took advantage of three interceptions from Chicago's Caleb Hanie to beat the Bears 25-20 Sunday.

Carson Palmer threw for 301 yards and Michael Bush iced the game with a touchdown run in the fourth quarter to lead the Raiders (7-4) to their third straight win against a Bears team missing starting quarterback Jay Cutler.

The Raiders settled for field goals on their first six trips inside the Chicago 30 before Bush's 3-yard run made it 25-13 with 3:47 to play.

Hanie struggled in his first career start for the Bears (7-4) in place of Cutler, who broke his right thumb last week in Chicago's sixth straight win to put a major obstacle into what had been a promising season. Hanie, who nearly led a comeback in last season's NFC title game, had thrown only 14 regular season passes since signing as an undrafted free agent in 2008 and looked like a career backup for much of this game.

Hanie completed 18 of 35 passes for 254 yards and three interceptions, including a crushing one late in the first half when the Bears were deep in Oakland territory and on the verge of taking the lead.

But Hanie also threw two TD passes, including a 5-yarder to Kellen Davis with 2:11 to play that cut the deficit to 25-20. That was set up by an 81-yarder to Johnny Knox.

The game ended when Hanie botched a spike play with 4 seconds left at his 46. Instead of immediately spiking the ball to stop the clock, he took an extra step back and hesitated, leading to a game-ending intentional grounding call.

Bush was held to 69 yards on the ground by Chicago's strong defense and Palmer was sacked four times and threw an interception as the Raiders missed injured big-play threats Darren McFadden, Jacoby Ford and Denarius Moore.

But they still managed to maintain their hold on first place in the AFC West by winning their third straight game, getting field goals of 40, 47, 42, 19, 37 and 44 yards to break the team record Janikowski shared with Jeff Jaeger.

They were also helped by another big-legged kicker. With Oakland at its own 20 early in the fourth quarter and Devin Hester set for a return, Shane Lechler punted the ball over Hester's head and it rolled into the end zone for a team-record 80-yard punt.

Hanie managed to drive the Bears into field goal range on that drive and Robbie Gould's 53-yard field goal cut Oakland's lead to 18-13 with 7:17 to play.

The Raiders answered with Palmer throwing a 47-yard pass to Louis Murphy on third-and-4 from midfield to set up Bush's touchdown.

Despite Hanie's interceptions, the Bears were still in the game trailing 12-7 at the break because the defense kept the Raiders out of the end zone.

Hanie's first interception came as he tried to throw the ball away but gave it right to Stanford Routt at the Bears 33. That set up Janikowski's second field goal to give Oakland a 6-0 lead.

Hanie erased that with two big plays on one drive in the second quarter. He scrambled 24 yards on a third-and-18 and then hit Knox on a 29-yard slant against the blitz on another third down for the touchdown that gave the Bears a 7-6 lead.

With Chicago down 9-7, Hanie had a second down at the Oakland 7. He attempted a throwback screen to Davis that was tipped by Aaron Curry and went right Kamerion Wimbley, who returned 83 yards before being dragged down by a horse-collar tackle by Lance Louis. Oakland settled for a 19-yard field goal.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/347875155d53465d95cec892aeb06419/Article_2011-11-27-Bears-Raiders/id-15c5c858f18246d089de214aad0db38b

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Tuesday, November 29, 2011

Kremlin candidate losing in South Ossetia election

South Ossetia's former education minister and presidential candidate Alla Dzhioyeva speaks at a central election commission in Tskhinvali, the regional capital of Georgia's breakaway province of South Ossetia, Monday, Nov. 28, 2011. The local election commission chief said that with 74 of 85 precincts counted, ex-education minister Alla Dzhioyeva has won 56.7 percent of Sunday's vote while Emergencies Minister Anatoly Bibilov got 40 percent. (AP Photo/Musa Sadulayev)

South Ossetia's former education minister and presidential candidate Alla Dzhioyeva speaks at a central election commission in Tskhinvali, the regional capital of Georgia's breakaway province of South Ossetia, Monday, Nov. 28, 2011. The local election commission chief said that with 74 of 85 precincts counted, ex-education minister Alla Dzhioyeva has won 56.7 percent of Sunday's vote while Emergencies Minister Anatoly Bibilov got 40 percent. (AP Photo/Musa Sadulayev)

A man walks with his child in snow in Tskhinvali, the regional capital of Georgia's breakaway province of South Ossetia, Monday, Nov. 28, 2011. (AP Photo/Musa Sadulayev)

(AP) ? An opposition candidate appeared Monday to have won a presidential election in the breakaway Georgian province of South Ossetia, defeating the Kremlin's chosen candidate in the Russia-allied enclave.

Former Education Minister Alla Dzhioyeva was leading with about 57 percent of Sunday's run-off vote against 40 percent for Emergencies Minister Anatoly Bibilov with ballots from 74 of the 85 precincts counted, the South Ossetian election commission said.

Both candidates had called for close ties with Russia.

Bibilov, who had the support of Russia's dominant pro-Kremlin party, refused to concede and complained to a court about alleged violations.

Bibilov was endorsed by outgoing separatist leader Eduard Kokoity, a two-time president who declared South Ossetia's independence following the brief 2008 war between Russia and Georgia over the province.

After the conflict, Moscow expanded its military presence in the South Caucasus region located between the Caspian and Black seas and pledged to restore South Ossetia's economy and infrastructure.

South Ossetia broke away from Georgia's central government during a war in the early 1990s, and many here hoped the declaration of independence would bring international recognition and economic development to the province of 60,000 people, which relies heavily on agriculture and Russian aid.

But living standards deteriorated rapidly due to economic isolation and sanctions from Georgia, while only four countries ? Russia, Venezuela, Nicaragua and the South Pacific island nation of Nauru ? have recognized South Ossetian as an independent country.

Critics accused Kokoity's government of embezzling Russian aid, while thousands of South Ossetians continue to live in half-destroyed houses and apartment buildings with irregular water and electricity supplies.

Dzhioyeva pledged to fight corruption and make the process of distributing Russian aid transparent.

Both candidates won some 25 percent of the vote in the first round of the election two weeks ago.

An expert on the region said that Bibilov's loss showed the limits of Russia's influence.

"Despite its status as a great power, Russia cannot install the candidate it needs in a tiny unrecognized republic whose dependence on Moscow's will is 100 percent," Pavel Svyatenkov was quoted as saying by the Kommersant daily on Monday.

___

Associated Press writers Misha Dzhindzhikhashvili in Tbilisi, Georgia, and Mansur Mirovalev in Moscow contributed to this report.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/cae69a7523db45408eeb2b3a98c0c9c5/Article_2011-11-28-EU-Georgia-South-Ossetia-Election/id-13f7f34f829747489da744e7eeef5e5e

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If you raise the price, they'll still come (AP)

NEW YORK ? The way Americans are chomping Big Macs, lacing up pricey sneakers and gulping peppermint mochas in this economy, you'd think they're taking advantage of big holiday discounts.

The truth is they're paying more.

McDonald's, Nike, Starbucks and other companies initially worried that customers would run the other way when they started raising prices to offset their higher costs for ingredients, fuel and packaging. But so far, cash-strapped Americans largely have swallowed the price spikes. And they're continuing to do so during this holiday shopping season.

On a recent weekday, five full floors of shoppers in a Nike store in New York didn't seem to mind paying more for their favorite kicks, including the almost $200 sneakers named for NBA star LeBron James. At a McDonald's across town, people munched on Big Macs and fries that cost a dime or two more than last year. Customers also piled into a Starbucks down the street, where cappuccinos and many other specialty drinks now top $5.

Timothy and Katrin Sullivan, a San Diego couple, estimate that together they spend about $100 a month on skinny caramel macchiatos and pumpkin spice lattes at Starbucks, where prices on some drinks have risen in some regions this year. As parents of five children, they worry about the economy and have cut back on travel and ball games, but so far their morning cup of joe has survived the chopping block despite the rising price.

"It's cheaper than therapy," says Katrin Sullivan, 39.

The prices Americans pay for food, travel and other things have steadily risen this year, according to government data. Prices went up 3.5 percent in October compared with the same month a year ago. At the same time, every month for the past year except one, spending grew 2 percent or more compared with the same month a year ago. That's given retailers some cautious optimism as they try to gauge just how much more consumers are willing to pay.

Pete Bensen, McDonald's chief financial officer told analysts during the company's earnings call that the question boils down to this: "Is the consumer in a place that we're comfortable we can continue to add price increases?"

Companies of all stripes have been asking that question a lot. In the past year, they've been paying more for materials like beef, corn and fuel that they use to make, package and transport their goods. A combination of poor crop yields in some parts of the world, unrest in the Middle East and greater demand from countries like Brazil and China have sent those costs up.

Many costs have come down after spiking in the spring. A pound of coffee, for example, is trading at about $2.30, down from $3 in the spring. But that's up from $2 a year ago.

As a result, Starbucks Corp. this year raised the price of the packaged coffee in its stores by 17 percent. The company declines to say whether prices on brewed drinks have risen or fallen overall in the past year, since those price decisions vary by region. But generally, the Seattle chain says the prices of specialty drinks like lattes and macchiatos are more likely to have risen this year than simpler drinks.

The price of a 16-ounce grande cappuccino at Starbucks costs about $4.25, up about 23 percent from $3.45 a year ago, research firm Technomic estimates. Meanwhile, a bagel went up from $1 a year ago to $1.25.

That hasn't stopped Starbucks customers from getting their coffee fix, though. Store traffic rose 6 percent in the most recent fiscal year, which ended in October. Revenue at stores open at least a year ? an indicator of a retailer's health ? rose 8 percent.

"We think we are in a very good spot right now," Jeff Hansberry, who runs Starbucks' consumer products division, said in a call with analysts this month.

At Nike Inc., sales rose almost 18 percent in the three-month period through August, even though it raised prices on certain styles this year. Nike hasn't detailed the price increases, but according to research firm SportsOneSource Group, the suggested price of a pair of this year's version of LeBron James' sneakers is about $170, up from about $160 last year. Nike said it expects to raise prices more broadly in the spring.

"We have not seen any big price resistance at all," Charles Denson, president of the Nike Brand, said in a call with analysts.

Likewise, traffic and sales grew after McDonald's raised prices an average of 1 percent in March and another 1.4 percent in May. In the third quarter, guest count increased 2.6 percent. Revenue at stores open at least a year rose 5 percent. (The revenue figure is a snapshot of money spent on food at both company-owned and franchised restaurants. It does not reflect corporate revenue.)

McDonald's won't give details on which items it raised prices on, but Technomic estimates that a Big Mac costs an average of $3.39, up from $3.19 a year ago. A large order of fries is about $1.89, up from $1.79.

And the company signaled that there may be more increases to come. "We will continue to evaluate additional price increases," said Bensen, McDonald's CFO, during a call last month. "As we look into 2012, we expect commodity cost increases in the U.S. to be similar to this year's."

Even if the costs for some raw materials decline, companies are still expected to continue to raise prices during this holiday shopping season. That's because costs for materials are uncertain, so companies will try to raise prices whenever they think customers will tolerate them. Still, they have to tread lightly or risk losing customers.

To be sure, families have trimmed their budgets as the economy plummets. But Americans continue to spend for myriad reasons, even though prices have risen on everything from Coca-Cola soda to Huggies diapers to Ben & Jerry's ice cream.

Some are stomaching the higher prices only on products they need. Others who've cut back on bigger frills are willing to splurge on brands they trust or things they see as small indulgences. Still others are apathetic to the increases because "everybody's doing it."

The weak economy has forced Kenya Leach, a New York actress, to cut back on eating out and trips to the movies and to reconsider her plans to return to school for an anthropology degree. Still, she keeps buying beauty products from Origins, which sells $35 moisturizer and $25 face wash, even though she's noticed those prices edge up by about a dollar per product, by her calculations.

Estee Lauder, the high-end cosmetics company that owns Origins, did not detail its price increases. But CEO Fabrizio Freda said recently during an analyst call that customers have been "resilient" as the company has raised prices and rolled out more expensive products.

Leach, for one, figures it's OK to spend a little more on Origins products because she is cutting out so many other things. "Treating yourself sends off those happy pheromones," says Leach, 25. "When I get really crabby and upset, I'll buy a new lipstick and I'll feel 10 times better."

Source: http://us.rd.yahoo.com/dailynews/rss/topstories/*http%3A//news.yahoo.com/s/ap/20111127/ap_on_bi_ge/us_willing_to_splurge

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Monday, November 28, 2011

An unexpected player in a cancer defense system

ScienceDaily (Nov. 28, 2011) ? Researchers of Karolinska Institutet and the University of Cologne, Germany, have identified a new protein involved in a defense mechanism against cancer. The VCP/p97 complex is best known for its role in protein destruction and is involved in a type of familial dementia and ALS. In a novel study the researchers now describe how this complex also plays an important role in regulating the recruitment of the tumor suppressor protein 53BP1 to damaged DNA -- suggesting an important role for VCP/p97 in our body's defense against cancer.

Damage of DNA is potentially very dangerous and linked to the development of cancer. Since DNA damage is unavoidable, our cells are equipped with a sophisticated defense system that activates repair mechanisms. This process is initiated by binding of sensor proteins to the damaged DNA that in turn bind and activate other proteins responsible for repairing the damage. During the last decade, it has become clear how many of those proteins are recruited to the damaged DNA, but the mechanism by which the tumor suppressor 53BP1 finds its way has been puzzling.

The surprising finding of this study, presented in the scientific journal Nature Structural & Molecular Biology, is not only the identity of the new player but also how it is doing the job. By following proteins in cells with DNA damage, the researchers found that the VCP/p97 complex is among the proteins that are being recruited to DNA damage. This was unanticipated since VCP/p97 is known to be primarily involved in the destruction of defective proteins. VCP/p97 is doing this by unwinding them so that the waste proteins can be chopped in pieces by dedicated enzymes. This important function also explains its involvement in a type of familial dementia and ALS since this kind of waste proteins typically pile up in these diseases.

It turns out that VCP/p97 is doing something similar at damaged DNA although with a very different outcome. The work shows that VCP/p97 facilitates the binding of 53BP1 by removing a protein that occupies the places where 53BP1 can bind. So instead of unwinding a protein to prepare it for destruction, VCP/p97 pulls a protein out of the way for 53BP1. The researchers also show that worms that have less of this complex are very sensitive to DNA damage supporting an important and evolutionary conserved role of VCP/p97 in DNA damage control. This new mechanism of recruiting a protein by removing another one that gets in the way sheds new light onto how the tumor suppressor 53BP1 finds damaged DNA. An important question that remains is if VCP/p97 plays similar roles in other processes.

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The above story is reprinted from materials provided by Karolinska Institutet.

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Journal Reference:

  1. Klara Acs, S. Martijn Luijsterburg, Leena Ackermann, Florian A. Salomons, Thorsten Hoppe & Nico P. Dantuma. The AAA-ATPase VCP/p97 promotes 53BP1 recruitment by removing L3MBTL1 from DNA double-strand breaks. Nature Structural & Molecular Biology, November 27 2011 DOI: 10.1038/10.1038/nsmb.2188

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://www.sciencedaily.com/releases/2011/11/111128115256.htm

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President brings daughters to bookstore to promote small-business holiday shopping (Star Tribune)

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Sunday, November 27, 2011

Thousands queue in Indonesia to buy new Blackberry (AP)

JAKARTA, Indonesia ? Thousands of Indonesians jammed into a glitzy shopping mall Friday to get hold of the first BlackBerry Bold 9790s being sold worldwide.

Fearing a riot, hundreds of police were deployed outside, tying up traffic in the heart of the capital for hours.

With a 50 percent discount on the $540 phone for the first 1,000 buyers, lines started forming in front of Pacific Place mall on Thursday night. By daybreak, impatient shoppers started rattling the gates.

And when rumors spread that the new smartphones ? commonly known as Bellagio ? had already sold out, the crowd of 3,000 went crazy. Several people fainted in the crush.

Indonesia, a nation of 240 million people, has experienced a come-from-nowhere tech frenzy in recent years.

With 6 million users, BlackBerry dominates the smartphone market.

Source: http://us.rd.yahoo.com/dailynews/rss/personaltech/*http%3A//news.yahoo.com/s/ap/20111125/ap_on_hi_te/as_indonesia_blackberry_frenzy

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